Testable hypotheses for cancer risks near nuclear facilities
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چکیده
Clarification of hypotheses can improve research design, measurements, data analysis, and interpretation of results. I will describe how hypotheses could be clarified during the design of an epidemiologic study of cancer risks near nuclear facilities in the United States. Based on what is known about age variation in radiation sensitivity and difficulties in evaluating other cancer risk factors and tracking people over long time periods, my conclusion is that knowledge about this topic can be most effectively advanced by studying childhood cancer incidence and in utero exposures.
منابع مشابه
Cancer Risks near Nuclear Facilities: The Importance of Research Design and Explicit Study Hypotheses
BACKGROUND In April 2010, the U.S. Nuclear Regulatory Commission asked the National Academy of Sciences to update a 1990 study of cancer risks near nuclear facilities. Prior research on this topic has suffered from problems in hypothesis formulation and research design. OBJECTIVES We review epidemiologic principles used in studies of generic exposure-response associations and in studies of sp...
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تاریخ انتشار 2010